12th Vitreoretinal Symposium Frankfurt – Marburg 2009
Scientific programm: Abstract
1st scientific session: Interface Macular Hole
5. Spectral Domain OCT 
     –  Critical Evaluation of Different Systems
Peter K. Kaiser (Cleveland)
  Few people realize that optical coherence tomography (OCT) was not even a  secondary endpoint in the pivotal, multicenter clinical trials for ranibizumab  (Lucentis, Genentech, South San    Francisco, CA). It  was an after-thought that was performed at a few select centers. However, in  the era of anti-VEGF agents, physician now use OCT in almost every case of age  related macular degeneration (AMD) and other retinal vascular diseases such as  diabetic retinopathy and retinal vascular occlusions, with a consequent  dramatic drop in our use of fluorescein angiography. Until recently, we relied  on interpreting time-domain OCT scans from the Stratus OCT (Carl Zeiss Meditec,  Dublin, CA).  The recent introduction of spectral domain OCT (SD-OCT) has dramatically  increased acquisition speed and improved axial resolutions. SD-OCT offers  several truly revolutionary improvements over Stratus for physicians. This  lecture will critically compare the new SD-OCT systems including the Bioptogen  3D SDOCT (Bioptogen, Raleigh, NC), Heidelberg Spectralis (Heidelberg  Engineering, Heidelberg, Germany), Topcon 3D OCT-1000 (Topcon Inc., Paramus,  NJ), Opko Spectral OCT/SLO (Opko, Miami, FL), Cirrus (Carl Zeiss Meditec,  Dublin, CA), Canon/Optopol Copernicus and Copernicus HR (Optopol, Poland), and  the RTVue-100 (Optovue, Freemont, CA). Features, advantages, and disadvantages  will be discussed.
  
  Financial Disclosure: 
  Dr Kaiser  serves on the scientific advisory boards of Carl Zeiss Meditec and Heidelberg  Engineering.
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